Nerve Regeneration by Wild Mushroom Lion’s Mane

Out of the kitchen, into the pharmacy, the gourmet mushroom Lion’s Mane (Hericium erinaceus) with its unique flavor resembling lobster or shrimp appears to also possess likewise unique medicinal properties. It has been found to stimulate nerve and myelin regeneration, which may be beneficial in many neurological conditions. World renowned medicinal mushroom expert Paul Stamets suggests its potential application in conditions such as Alzheimer’s, dementia, multiple sclerosis and muscular dystrophy. [134]

Lion’s Mane Mushroom (Hericium erinaceus) is known in the wild from North America, Europe, China and Japan. It grows on many species of deciduous trees, in particular oak, walnut, beech, maple and sycamore.

The active compounds that have received the most attention for their nerve regenerating properties are named erinacines, a series of low molecular weight molecules that are able to pass through the blood brain barrier – an essential attribute for any medicinal compound expected to be able to effect healing on myelin or nerve tissue. [152, 153, 154]

In Japan, there are two patents on extracts of Hericium erinaceus. The first was filed in the 1990′s for a process of extraction that yields what has been named “Nerve Growth Stimulant Factor.” [150, 151] The second from 2004 is for a water extract of Hericium erinaceus. It is likewise used to stimulate nerve regeneration. [155]

In Traditional Chinese Medicine (TCM), Hericium erinaceus has historically been prescribed not only for neurological conditions but also for ailments of the digestive tract, in particular for cancers of the digestive organs, such stomach cancer and liver cancer.

Modern science has provided some support for this traditional use of Hericium erinaceus extract. One study conducted in 1985 reported positive results for treating atrophic gastritis. Another, published in 1995, presented findings that Hericium erinaceus helped extend the average life expectancy for patients with hepatoma. [156]

Finally, a few additional areas where modern research has reported benefits from the use of Hericium erinaceus extract include: Anti-tumoral [159]; stomach cancer [134]; inflammation [134]; immune support [157]; antimicrobial against Aspergillus and Candida. [158]

Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Always consult a licensed medical practitioner before using any herb (or mushroom) for medicinal purposes.

Credits: Thank you, Paul Stamets, for research references.

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